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These are the excellent presentations from the Children with Cancer UK sponsored childhood cancer session organised by Professor Denis Henshaw for the 8th Princess Chulabhorn International Scientific Congress held in Thailand in November 2016.

Professor Thomas Seyfried

Professor Thomas Seyfried

Ph.D., University of Illinois, Urbana-Champaign
Professional page on the Biology department at Boston College
Author of Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer

CC2018 Talk Abstract


Our research program focuses on mechanisms by which metabolic therapy manages chronic diseases such as epilepsy, neurodegenerative lipid storage diseases, and cancer. The metabolic therapies include caloric restriction, fasting, and ketogenic diets. Our approach is based on the idea that compensatory metabolic pathways are capable of modifying the pathogenesis of complex diseases. Global shifts in metabolic environment can neutralize molecular pathology. In the case of cancer, these therapies target and kill tumor cells while enhancing the physiological health of normal cells. The neurochemical and genetic mechanisms of these phenomena are under investigation in novel animal models and include the processes of inflammation, cellular physiology, angiogenesis, and lipid biochemistry.

Seyfried TN, Cancer as a mitochondrial metabolic disease, Front Cell Dev Biol. 2015 Jul 7;3:43. doi: 10.3389/fcell.2015.00043

Editorial Boards

ASN NEURO, Senior Editor
Journal of Lipid Research
Neurochemical Research
Nutrition & Metabolism


Alumni Achievement Award, University of New England, 2013
Lifetime Achievement Award, 2016 - Academy of Comprehensive and Complementary Medicine
Mercola Gamechanger Award, 2016
American College of Nutrition Award Lecture winner, 2017

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